(R)-Baclofen Hydrochloride - CAS# 63701-55-3 iazole Genome-wide analysis in Jurkat T-ALL

Genome-wide analysis in Jurkat T-ALL cells shows that THZ1 disproportionally affects transcription of RUNX1 and suggests that sensitivity to THZ1 may be due to vulnerability conferred by the RUNX1 super-enhancer and the key role of RUNX1 in the core transcriptional regulatory circuitry in these tumor cells

7-dimethyl-2-oxo-1-bicyclo[2

Formula: C36H62O8

CAS Number: 2172819-72-4

Smiles: OC(=O)C1=CC(=CC=C1O)N(CC1=CC=CC=C1O)CC1=CC=CC=C1O

(R)-Baclofen Hydrochloride - CAS# 63701-55-3 iazole Genome-wide analysis in Jurkat T-ALLArbaclofen hydrochloride is a Gamma Aminobutyric Acid derivative that is a specific agonist at GABA B receptors (RECEPTORS, GABA B). It is used in the treatment of spasticity, especially that due to spinal cord damage. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission. Product information CAS Number: 63701 55 3 Molecular Weight: 250. 12 Formula: C10H13Cl2NO2 Synonym: STX 209